Storage Requirements
Mounjaro must be kept refrigerated at:
- Store in a refrigerator — not in the door, which can experience temperature fluctuations
- Keep in the original packaging and away from direct light
- Do not freeze — freezing permanently damages the formulation
- Once removed from the fridge, refer to the patient information leaflet for room temperature time limits
These requirements apply throughout the entire supply chain from the manufacturer, to the pharmacy, through delivery, and into your home. Failure at any point can compromise medication safety and effectiveness.
What Safe Delivery Looks Like
A proper cold chain delivery from a GPhC registered pharmacy should include:
- Insulated packaging — typically a polystyrene box or specialist insulated bag
- Ice packs or gel packs — to maintain temperature during transit
- Cool temperature on arrival — the packaging and medication should feel cold when opened
The packaging should also be sealed, tamper evident, and include your prescription details and patient information leaflet. If any of these elements are absent, contact the pharmacy before using the medication.
What If It Gets Warm?
Temperature excursions during delivery are rare when using a compliant pharmacy, but they do occur. The Mounjaro SmPC provides clear guidance on what to do:
2–8°C
Refrigerated — fully safe for use
8–30°C
Room temperature — usable within time limit (check leaflet)
Above 30°C
Unsafe — do not use, contact pharmacy
If the medication has been exposed to temperatures above 30°C, do not use it. Contact your pharmacy to report the issue and request a replacement. Keep the packaging as evidence of the temperature breach.
Warning Signs
Be cautious if your delivery shows any of the following signs of inadequate cold chain handling:
- No insulation — the package is a standard cardboard box or envelope with no thermal lining.
- Warm packaging on arrival — the contents should feel cold, not room temperature.
- Melted or absent ice packs — indicates the cold-chain may have failed during transit.
- Poor or absent packaging — if the pen is not in its original box, or the patient information leaflet is missing, contact the pharmacy before use.
- No GPhC registration displayed — legitimate pharmacies are legally required to show their registration. Verify at the GPhC register.
These warning signs are also indicators of an unregistered or unverified supplier. Our pharmacy verification guide explains the checks that distinguish compliant providers from unsafe ones. All pharmacies listed on Health Wise are verified against these standards before listing.
Related Guides
Browse more topics in our helpful guides hub.
Sources & Further Reading
This guide references the following official and authoritative sources.
- 1Mounjaro (tirzepatide) SmPC — storage and handling
Official prescribing reference confirming storage requirements of 2°C–8°C refrigerated, and the 21-day room temperature rule below 30°C.
- 2MHRA — Cold chain guidance for medicines
MHRA guidance on the transport and storage of temperature-sensitive medicines in the UK supply chain.
- 3NHS — Tirzepatide (Mounjaro) — storage information
NHS patient information on how to store and handle Mounjaro correctly at home.
- 4GPhC — Standards for registered pharmacies: premises and equipment
GPhC standards requiring pharmacies to maintain appropriate storage conditions for all dispensed medicines.
- 5How we verify UK pharmacies — Health Wise
How Health Wise checks cold-chain compliance for every pharmacy listed on our platform.





